Needle Biopsy of the Prostate: Post Discharge Instructions

What to Expect After Needle Biopsy

After the procedure, your doctor may prescribe an antibiotic. If you do not receive a prescription prior to leaving the office or clinic, please ask your recovery nurse. Make sure that you take the medication as directed. Complete the prescription. Avoid using aspirin or other blood thinners for one week after biopsy to avoid bleeding.

  • It is normal to have blood in your urine for 3 or 4 days and possibly light rectal bleeding.
  • To clean out the urinary tract, drink four to six 8-ounce glasses of water daily for 3 to 4 days. If you are passing large blood clots, call your doctor.
  • It is normal to experience burning on urination for 24 hours after the biopsy. If you are having trouble urinating, try to urinate in warm baths. This may alleviate your discomfort.
  • After the procedure, some men complain of a clear to brownish discharge from the penis. You may notice blood in your semen (sperm) for up to 1 month afterward.
  • If you have nausea, vomiting, shaking chills, a fever greater than 101.4° F, within the first 24 hours following the biopsy, call the doctor immediately (day or night).
  • You should not do any heavy lifting for 24 hours. Do not strain during a bowel movement for 48 hours.
  • Call for a follow-up appointment.

When should you call your doctor?

  • Your temperature rises above 101.4° F
  • You have nausea, vomiting, or shaking chills
  • You are experiencing burning on urination or are passing blood clots
  • You are unable to urinate when you feel that your bladder is full
  • You develop a reaction to your medication such as skin rash, nausea, or vomiting