Emergencies

 

Some urological conditions have serious or life-threatening consequences and require immediate medical attention. These medical emergencies include:
 
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Acute urinary retention
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Fournier’s gangrene
While these conditions are unrelated and have different symptoms, they all require urgent care. Delaying treatment in some cases can result in surgical removal of testicles (orchiectomy), permanent inability to achieve an erection (impotence), or death.

Acute Urinary Retention
Acute urinary retention is the sudden inability to urinate and is usually symptomatic of another condition that needs treatment.

Incidence and Prevalence
Anyone can experience acute urinary retention. The causes and rate of occurrence varies greatly between genders until about age 60, when men are more often affected as a result of benign prostatic hyperplasia (BPH).

Risk Factors
Kidney stones, prostate cancer, prostatitis, and BPH are risk factors in men. Women with a history of kidney stones or urinary tract infections (UTIs), pregnant women, and those who have had recent gynecological surgery are at higher risk.

Causes
Acute urinary retention is caused by obstruction in the bladder or the tube that carries urine from the bladder outside the body (urethra), a disruption of sensory information in the nervous system (e.g., spinal cord or nerve damage), or a situation or event that causes the bladder to become distended.

Factors associated with acute urinary retention include the following:
Alcohol consumption
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Allergy or cold medications containing decongestants or antihistamines
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Certain prescription drugs (e.g., ipratropium bromide, albuterol, epinephrine) that cause the urethra to become narrow
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Delaying urination for a long time
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Long period of inactivity or bed rest
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Prolonged exposure to cold temperatures
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Spinal cord injury/nerve damage
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Surgery (e.g., complication of anesthesia)
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Urinary system obstruction (e.g., benign prostatic hyperplasia (BPH), kidney stones)
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urinary tract infection
Signs and Symptoms
Acute urinary retention produces severe lower abdominal pain, a distended abdomen, and/or the sudden inability to pass urine.

Complications that may develop with untreated urinary retention include bladder damage and chronic kidney failure.

Diagnosis
Diagnosis is based on a sudden lack of urinary output and bladder swelling (distention) observed during a physical examination.

Treatment
Treatment should be obtained within 5 hours of the onset of symptoms to avoid the development of complications. The underlying cause of urinary retention (e.g., kidney stones) must be diagnosed and treated as well.

A small tube (catheter) is inserted into the bladder through the urethra to drain the urine. Catheterization relieves pain and distention.

Prognosis
Depending on the underlying cause, the recurrence rate can be up to 70% within a week after initial treatment. BPH is responsible for most recurrences.
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Fournier’s Gangrene
Fournier’s gangrene, sometimes called Fournier’s disease, is a bacterial infection of the skin that affects the genitals and perineum (i.e., area between the scrotum and anus in men and in women between the vulva and anus). The disease develops after a wound or abrasion becomes infected. A combination of anaerobic (living without oxygen) microorganisms (e.g., staphylococcal) and fungi (e.g., yeast) causes an infection that spreads quickly and causes destruction (necrosis) of skin, tissue under the skin (subcutaneous tissue), and muscle. Staphylococcal bacteria clot the blood, depriving surrounding tissue of oxygen. The anaerobic bacteria thrive in this oxygen-depleted environment and produce molecules that instigate chemical reactions (enzymes) that further the spread of the infection. Fournier’s gangrene can be fatal if the infection enters the bloodstream.

Incidence and Prevalence

Men are ten times more likely than women to develop Fournier’s gangrene. Men aged 60-80 with a predisposing condition are most susceptible.

Women who have had a pus-producing bacterial infection (abscess) in the vaginal area, a surgical incision in the vagina and perineum to prevent tearing of skin during delivery of a child (episiotomy), an abortion resulting in fever and an infection of the lining of the uterus (septic abortion), or surgical removal of the uterus (hysterectomy) are susceptible.

Rarely, children may develop Fournier’s gangrene as a complication in wounds that result from a burn, circumcision, or insect bite.

Risk Factors

Men with alcoholism, diabetes mellitus, leukemia, morbid obesity, and immune system disorders (e.g., HIV, Crohn’s disease), and intravenous drug users are at increased risk for developing Fournier’s gangrene. Surgery is also a risk factor.

Causes
Fournier’s gangrene develops when multiple bacteria infect the body through a wound, usually in the perineum, tube that carries urine outside the body from the bladder (urethra), or colorectal area. Existing immune system deficiencies help infection to spread quickly, producing a disease that destroys the skin and superficial and deep fascia (membranes that separate muscles and protect nerves and vessels) of the genital area. The chambers in the penis that fill with blood to create an erection (corpora cavernosa), testicles, and urethra are not usually affected.

Signs and Symptoms
The early physical symptoms of Fournier’s gangrene do not always indicate the severity of the condition. Pain sometimes diminishes as the disease progresses. Symptoms are progressive and include the following:
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Crepitant ("spongy" to the touch) skin
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Dead and discolored (gray-black) tissue; pus weeping from injury
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Fever and drowsiness (lethargy)
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Increasing genital pain and redness (erythema)
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Odor
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Severe genital pain accompanied by tenderness and swelling of the penis and scrotum
Diagnosis
Physical examination and blood tests are necessary. A diagnosis is made on finding gangrenous (i.e., spongy, weeping, discolored) skin. Microscopic examination of a tissue specimen (biopsy) may be taken if visible symptoms are insufficient to distinguish between Fournier’s and other bacterial infections.

Treatment
Antibiotics (often double or triple drug therapy) along with aggressive surgical removal of all of the diseased tissue is required immediately for an optimal outcome.

Without early treatment, bacterial infection enters the bloodstream and can cause delirium, heart attack, respiratory failure, and death.

Complications
Incomplete debridement (surgical removal of dead tissue) allows wound infection to continue to spread. In this event, follow-up surgery is performed.
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For more information about The Austin Diagnostic Clinic's urology department or this topic, please call 512/901-4021.

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