Dermatology, The Austin Diagnostic Clinic

   

Malignant Melanoma

 
This most virulent of all skin cancers will develop on the skin of an estimated 27,300 Americans in 1998. An estimated 5,800 will die. It is important to note that the death rate is at last declining, because patients are seeking help earlier. Melanoma, like its less aggressive cousins, basal cell and squamous cell carcinomas is almost always curable in its early stages. Melanoma has its beginnings in melanocytes; the skin cells, which produce the dark protective pigment, called melanin, which is responsible for suntanned skin acting as a partial protection against the sun. Melanoma cells usually continue to produce melanin, which accounts for the cancers appearing in mixed shades of tan, brown and black. Melanoma has a strong tendency to spread, making it more difficult to treat.

Melanoma may suddenly appear without warning but it may also begin in or near a mole or other dark spot in the skin. For that reason it is important that we know the location and appearance of the moles on our bodies so any change will be noticed.

Excessive exposure to the sun, as with the other skin cancers, is accepted as a cause of melanoma, especially among light-skinned people. Heredity may play a part, and also atypical moles, which may run in families, can serve as markers, identifying the person as being at higher risk for developing melanoma there or elsewhere in the skin.

Dark brown or black skin is not a guarantee against melanoma. Black people can develop this cancer, especially on the palm of the hands, soles of the feet, under nails, or in the mouth.

The abcds of Melanoma

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Asymmetry. One half doesn't match the other half. Border irregularity. The edges are ragged, notched or blurred. Color. The pigmentation is not uniform. Shades of tan, brown and black are present. Dashes of red, white and blue add to the mottled appearance. Diameter greater than six millimeters (about the size of a pencil eraser). Any growth in size of a mole should be of concern.

Some additional warning signs of melanoma would include changes in the surface of a mole: scaliness, oozing, bleeding or the appearance of a bump or nodule; spread of pigment from the border into surrounding skin; and change in sensation including itchiness, tenderness, or pain.


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